Histamine and Antihistaminic Agents
نویسنده
چکیده
Histamine is an β–imidazolylethylamine derivative that is present in essentially all mammalian tissues. The major physiological actions of histamine are centered on the cardiovascular system, nonvascular smooth muscle, exocrine glands and the adrenal medulla. In a general sense, histamine plays an important role as a “chemical messenger” component of the various pathways that have evolved in multicellular organisms allowing them to communicate efficiently and effectively. The involvement of histamine in the mediation of allergic and hypersensitivity reactions as well as in the regulation of gastric acid secretion has led to the development of important drug classes useful in the treatment of symptoms associated with allergic and gastric hypersecretory disorders.
منابع مشابه
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